If co-administration of mitigare and a cyp3a4 inhibitor is necessary, the dose of mitigare should be adjusted by either reducing the daily dose or reducing the dose frequency, and the patient should be monitored carefully for colchicine toxicity see clinical pharmacology .
Information about Colchicine.
arrow-down About colchicine arrow-down Before taking colchicine arrow-down How to how much colchicine for gout attack colchicine arrow-down Getting the most from your treatment arrow-down Can colchicine cause problems? arrow-down How to store how much colchicine for gout attack arrow-down Important information about all medicines.
Do not eat grapefruit or drink grapefruit juice during your treatment with colchicine.Gout Slideshow Pictures.
It is not known if colchicine capsules are safe and effective for the treatment of.
Advise patients that muscle pain or weakness.tingling or numbness in fingers or toes may occur with colchicine capsules alone or when it is used with certain other drugs. Patients developing any of these signs or symptoms must discontinue colchicine capsules and seek medical evaluation immediately.
Gastrointestinal disorders are the most common adverse reactions with colchicine. They are often the first signs of toxicity how much colchicine for gout attack may indicate that the colchicine dose needs to be reduced or therapy stopped. These include diarrhea.nausea.vomiting.and abdominal pain.
Clearance is decreased in renal and hepatic impairment. monitor for toxicity and adjust dose if necessary.
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