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The use of MEDROL Tablets in active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate antituberculous regimen.

Check with your doctor right away if blurred vision.difficulty in reading.eye pain.or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

MEDROL Tablets contain methylprednisolone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids.both naturally occurring and synthetic.which are readily absorbed from the gastrointestinal tract. Methylprednisolone occurs as a white to practically white.odorless.crystalline powder. It is sparingly soluble in alcohol.in dioxane.and in methanol.slightly soluble in acetone.and in chloroform.and very slightly soluble in ether. It is practically insoluble in water.

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before taking this medication, tell your doctor if you are taking any of the following medicines tricyclic antidepressants such as amitriptyline elavil, endep ; or doxepin sinequan ; , which may decrease the effects of chlorthalidone and reserpine; other commonly used tricyclic antidepressants, including amoxapine ascendin ; , clomipramine anafranil ; , desipramine norpramin ; , imipramine tofranil ; , nortriptyline pamelor ; , and protriptyline vivactil digoxin lanoxin ; or quinidine cardioquin, quinidex, quinora, quinaglute ; , which will increase the risk that you will experience an irregular heartbeat when it is taken with chlorthalidone and reserpine; barbiturates such as phenobarbital luminal, solfoton ; , amobarbital amytal ; , and secobarbital seconal ; , which may cause extreme sleepiness or dizziness if taken with chlorthalidone and reserpine; narcotic pain relievers such as codeine tylenol 3, tylenol 4, others about others , propoxyphene darvon, darvocet, wygesic ; , oxycodone percodan, percocet, tylox ; , meperidine demerol ; , morphine ms contin, duramorph, others ; , and others also may cause extreme sleepiness or dizziness if taken with chlorthalidone and reserpine; steroid medications such as hydrocortisone hydrocortone, cortef ; , prednisone deltasone, orasone ; , prednisolone delta cortef, prelone ; , methylprednisolone medrol ; , betamethasone celestone ; , dexamethasone decadron, hexadrol ; , and others, which may increase the side effects of chlorthalidone; prescription and over-the-counter cough, cold, allergy, diet, and sleeping pills, any of which may contain drugs that increase your blood pressure and heart rate and thus decrease the effects of reserpine; the cholesterol-lowering drugs cholestyramine questran ; and colestipol colestid ; , which may decrease the effects of; nonsteroidal anti-inflammatory drugs nsaids ; such as ibuprofen motrin, advil ; , ketoprofen orudis, orudis about orudis ; , kt, oruvail ; , and naproxen naprosyn, anaprox, aleve ; , which may also decrease the effects of chlorthalidone; other commonly usednsaids see also nsaids ; , including diclofenac cataflam, voltaren ; , etodolac lodine ; , fenoprofen nalfon ; , flurbiprofen ansaid ; , indomethacin indocin ; , ketorolac toradol ; , mefenamic acid ponstel ; , nabumetone relafen ; , oxaprozin daypro ; , piroxicam feldene ; , sulindac clinoril ; , and tolmetin tolectin oral antidiabetic drugs such as glipizide glucotrol ; , glyburide micronase, glynase, diabeta ; , chlorpropamide diabinese ; , tolazamide tolinase ; and tolbutamide orinase ; , which may not lower your blood sugar as well your diabetes therapy may have to be adjusted lithium lithobid, eskalith ; , should not be taken with chlorthalidone because serious side effects may result; or other drugs that also lower blood pressure, including acebutolol sectral ; , atenolol tenormin ; , bisoprolol zebeta ; , carteolol cartrol ; , labetalol trandate, normodyne ; , propranolol inderal ; , pindolol visken ; , timolol blocadren ; , benazepril lotensin ; , enalapril vasotec ; , captopril capoten ; , fosinopril monopril ; , lisinopril prinivil, zestril ; , moexipril univasc ; , quinapril accupril ; , ramipril altace ; , amlodipine norvasc ; , bepridil vascor ; , diltiazem cardizem, dilacor ; , felodipine plendil ; , isradipine dynacirc ; , nicardipine cardene ; , nifedipine adalat, procardia ; , nimodipine nimotop ; , and verapamil calan, verelan, isoptin.

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