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Adverse reactions appear to correlate with the size of the dose of INDOCIN in most patients but not all. Therefore.every effort should be made to determine the smallest effective dosage purchase indocin side the individual patient.

Taking Purchase indocin side during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Avoid the use of INDOCIN in patients with severe heart failure unless the benefits are expected to outweigh the risk of worsening heart failure. If INDOCIN is used in patients with severe heart failure.monitor patients for signs of worsening heart failure.

Clinical trials of several COX-2 selective and nonselective NSAIDs of up to three purchase indocin side duration have shown an increased risk of serious cardiovascular (CV) thrombotic events.including myocardial infarction (MI) and purchase indocin side.which can be fatal. Based on available data.it is unclear that the risk for CV thrombotic events is similar for all NSAIDs. The relative increase in serious CV thrombotic events over baseline conferred by NSAID use appears to be similar in those with and without known CV disease or risk factors for CV disease. However.patients with known CV disease or risk factors had a higher absolute incidence of excess serious CV thrombotic events.due to their increased baseline rate. Some observational studies found that this increased risk of serious CV thrombotic events began as early as the first weeks of treatment. The increase in CV thrombotic risk has been observed most consistently at higher doses.

Inform patients of the signs of an anaphylactic reaction (e.g..difficulty breathing.swelling of the face or throat). Instruct patients to seek immediate emergency help if these occur [see CONTRAINDICATIONS and WARNINGS AND PRECAUTIONS ].

Indomethacin is approved to treat. Moderate to severe osteoarthritis (wear-and-tear arthritis) Rheumatoid arthritis (inflammatory arthritis) Ankylosing spondylitis (inflammatory arthritis of the spine)

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

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