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Evaluable pd population all subjects in the pd population who completed the morphine naltrexone treatment and at least 1 other study treatment during the double-blind treatment phase.

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After taking naltrexone.your body will be more sensitive to opioids . If you use an opioid medicine in the future.you will need to use less than before naltrexone treatment. Using the same amount you used before could lead to overdose or death.

Do not use narcotic medication.heroin.or other street drugs while you are taking naltrexone . Never try to overcome the effects of naltrexone by taking large doses of opioids. Doing so could result in dangerous effects.including coma and death.

Data collected from postmarketing use of REVIA show that most events usually occur early in the course of drug therapy and are transient. It is not always possible to distinguish these occurrences from those signs and symptoms that may result from a withdrawal syndrome. Events that have been reported include anorexia.asthenia.chest pain.fatigue.headache.hot flushes.malaise.changes in blood naltrexone treatment.agitation.dizziness.hyperkinesia.nausea.vomiting.tremor.abdominal pain.diarrhea.palpitations.myalgia.anxiety.confusion.euphoria.hallucinations.insomnia.nervousness.naltrexone treatment.abnormal thinking.dyspnea.rash.increased sweating.vision abnormalities.and idiopathic thrombocytopenic purpura.

There are no systematically collected data that specifically address the switch from buprenorphine or methadone to REVIA. however.review of postmarketing case reports have indicated that some patients may experience severe manifestations of precipitated withdrawal when being switched from opioid agonist therapy to opioid antagonist therapy (see WARNINGS ). Patients transitioning from buprenorphine or methadone may be vulnerable to precipitation of withdrawal symptoms for as long as 2 weeks. Healthcare providers should be prepared to manage withdrawal symptomatically with non-opioid medications.

treat alcohol dependence. You should stop drinking before starting VIVITROL. prevent relapse to opioid dependence.after opioid detoxification.

Naltrexone might harm an unborn baby. You should talk to your doctor about using this medicine if you are pregnant or planning to become pregnant.

At present.naltrexone implants are not approved by FDA.and are naltrexone treatment available in clinical settings offering 24-hour monitoring and supervision.such as drug and alcohol naltrexone treatment facilities.

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in a meta-analysis of all placebo-controlled trials of naltrexone or acamprosate for alcoholism treatment, there were significant effects on treatment retention and or drinking outcomes.

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